Therapeutic Applications & Uses of CBD

Results of what has been studied are promising. CBD has many benefits, such as anti-inflammatory and neuroprotective properties. 

Some studies have found CBD may be effective in providing relief from various mental health conditions, including: 

It may be effective for physical conditions as well. Likewise, CBD has also been proven to help treat childhood epilepsy and other seizure disorders. Some evidence points to CBD’s anticancer properties and benefits in managing the side effects of cancer treatment.

More research is needed to determine the benefits of using CBD as a treatment for mental and physical health conditions.

Overview of diseases for which CBD may have therapeutic benefits.

Alzheimer’s diseaseAnti Inflammatory, antioxidant, antiapoptotic in in vitro and in vivo models of Aβ-evoked neuroinflammatory and neurodegenerative responses.
Parkinson’s diseaseAttenuation of the dopaminergic impairment in vivo; neuroprotection; improvement of psychiatric rating and reduction of agitation, nightmares and aggressive behaviour in patients.
Multiple sclerosisImproved signs of EAE in mice, anti-inflammatory and immunomodulatory properties.
Huntington’s diseaseNeuroprotective and antioxidant in mice transgenic models; no significant clinically important differences in patients.
Hypoxia-ischemia injuryShort term neuroprotective effects; inhibition of excitotoxicity, oxidative stress and inflammation in vitro and in rodent models.
PainAnalgesic effect in patients with neuropathic pain resistant to other treatments.
PsychosisAttenuation of the behavioural and glial changes in animal models of schizophrenia; antipsychotic properties on ketamine-induced symptoms
AnxietyReduction of muscular tension, restlessness, fatigue, problems in concentration, improvement of social interactions in rodent models of anxiety and stress; reduced social anxiety in patients.
DepressionAntidepressant effect in genetic rodent model of depression.
CancerAntiproliferative and anti-invasive actions in a large range of cancer types; induction of autophagy-mediated cancer cell death; chemopreventive effects.
NauseaSuppression of nausea and conditioned gaping in rats
Inflammatory diseasesAnti-inflammatory properties in several in vitro and in vivo models; inhibition of inflammatory cytokines and pathways.
Rheumatoid arthritisInhibition of TNF-α in an animal model
InfectionActivity against methicillin-resistant Staphylococcus aureus
Inflammatory bowel and Crohn’s diseasesInhibition of macrophage recruitment and TNF-α secretion in vivo and ex vivo; reduction in disease activity index in Crohn’s patients.
Cardiovascular diseasesReduced infarct size through antioxidant and anti-inflammatory properties in vitro and in vivo.
Diabetic complicationsAttenuation of fibrosis and myocardial dysfunction
Table 1. Overview of diseases for which CBD may have therapeutic benefits taken from Pisanti et al (2017) [69]